Longevity of Zygocotyle lunata in Balb/c mice and long-term survival of digeneans in vertebrate hosts

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Longevity of Zygocotyle lunata in Balb/c mice and long-term survival of digeneans in vertebrate hosts

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Title: Longevity of Zygocotyle lunata in Balb/c mice and long-term survival of digeneans in vertebrate hosts
Author: Fried, Bernard; LeSage, K. E.
Abstract: This study used Balb/c mice to examine the longevity of Zygocotyle lunata in a murine host. Of 11 mice, each exposed to 20 Z. lunata cysts, six were infected with a total of 12 worms from 11 to 24 weeks postinfection (PI). Live worms recovered at 24 weeks PI had a mean body area of about 25 mm(2). These worms produced viable eggs with well-developed miracidia following embryonation in artificial spring water for 2 weeks at 28 degrees C. The Balb/c mouse is a useful model to study longevity of this paramphistomid trematode for at least 6 months PI. An additional aspect of this article is a review of the pertinent literature published from 1937 to 2007 on ageing and longevity of digeneans.
URI: http://hdl.handle.net/10385/882
Date: 2011

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